Abstract

“AYURVEDA INSIGHTS INTO HUNGER AND SATIETY: CORRELATION OF KSHUDHA AND TRUPTI WITH NEUROENDOCRINE MECHANISMS”

*Dr. Chaudhary Mohammad Rayees Mohammad Halim, Dr. Hemangini Waghulade

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Abstract

Ayurveda, the ancient Indian system of medicine, offers a profound and holistic perspective on the intricate processes of Kshudha (hunger) and satiety (Trupti). While contemporary medicine primarily attributes these sensations to neuroendocrine mechanisms involving various hormones and neurotransmitters, Ayurvedic texts delineate a complex interplay of Agni (digestive fire), Doshas (bio-energies), and Dhatus (tissues) in regulating digestive function and metabolic equilibrium. This article explores the Ayurvedic understanding of Kshudha and Trupti, correlating these concepts with modern neuroendocrine physiology. It delves into the role of Jatharagni, Bhutagnis, and Dhatwagnis in digestion and metabolism, and examines how imbalances in Vata, Pitta, and Kapha Doshas influence appetite regulation. The missed study attempts to principles and the actions of key hunger- and satiety-regulating hormones such as ghrelin, leptin, cholecystokinin (CCK), glucagon-like peptide-1 (GLP-1), and insulin. By integrating these two distinct yet complementary frameworks, this article aims to provide a comprehensive understanding of hunger and satiety, paving the way for synergistic approaches to managing metabolic disorders and promoting overall well-being.

Keywords: Ayurveda, Kshudha, Trupti, Agni, Doshas, Neuroendocrine, Hunger, Satiety, Ghrelin, Leptin.