Abstract

MEDICATED LOZENGES: A COMPRESHIVE REVIEW ON FORMULATION AND APPLICATION

Monika G. B.*, Dr. Snehalatha, Maruthi N., Gagan G., Shalini B.

Abstract

Lozenges are solid medicated dosage forms containing a drug along with flavoring and Sweetening agents and are intended to be sucked and held in mouth or pharynx which dissolve or disintegrate slowly in the mouth. Development of lozenges dated back to 20th century and is still remain in the commercial production and have a bright future as novel method of delivering drugs for local and systemic effect lozenges provides the several advantages as pharmaceutical formulations however with some disadvantages. Lozenges as a dosage form can be adapted for drug delivery across buccal route, labial route, gingival route and sublingual route. Lozenges are of different types and are manufactured by different methods. Different types of lozenges available in market are compressed lozenges, hard lozenges & soft lozenges and their methods of preparation along with ingredients used in their preparation are discussed. The acceptance for lozenges as a dosage form is high by adults and also more by children. The present review covers more or less all aspects associated with lozenges it includes various research performed till date, advantages, disadvantages, classification, evaluation parameters, packing and application of lozenges.

Keywords: Lozenges, Oral Drug Delivery (ODD), dysphagia.