Abstract

A NARRATIVE REVIEW ON SPANLASTICS WITH POTENTIAL APPLICATIONS

*Shalini B., Dr. Snehalatha, Maruthi N., GB Monika, Gagan G.

.

Abstract

The Spanlastics are a new type of elastic vesicular nanocarrier that is based on surfactants and composed of spans and edge activators. In 2011, a novel medication delivery method known as Spanlastics was released. They are elastic, deformable, surfactant-based nanovesicles. These are the special class of nanovesicles that overcomes the disadvantages associated with liposomes, such as chemical instability. They provide targeting and controlled release of natural pharmaceutical compounds and have improved several drawbacks of the conventional dosage form. The current review emphasizes the utility of Spanlastics advantages, disadvantages, structure, classification, preparation approaches, mechanism of penetration, evaluation parameters and applications.

Keywords: Spanlastics, nanovesicles, edge activators, nonionic surfactants.