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World Journal of Pharmaceutical Research (WJPR) is giving Best Article Award in every Issue for Best Article and Issue Certificate of Appreciation to the Authors to promote research activity of scholar.
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Abstract

INTEGRATED AYURVEDIC MANAGEMENT OF COVID-19 WITH SPECIAL REFERENCE TO CYTOKINE STORM: A CASE SERIES

*Dr. Bhalchandra Mahamuni, Dr. Soniya Bhalchandra Mahamuni, Dr. Bhagyashree Purushottam Dhaskat

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Abstract

Background: The COVID-19 pandemic caused widespread morbidity and mortality, primarily due to cytokine storm induced multi-organ failure. Ayurveda offers a holistic understanding of this pathophysiology through the concepts of Vata Kaphaja Sannipata, Rasavaha Strotodushti, and Dhatwagni Mandya. Objective: To evaluate the role of Ayurvedic management in critical COVID-19 patients showing features of cytokine storm and desaturation, and to correlate Ayurvedic understanding with the modern cytokine storm mechanism. Methods: This case series includes three critical COVID-19 patients with oxygen saturation between 66–80%, HRCT score 17–20/25, and elevated inflammatory markers (CRP, LDH, Ferritin, D-Dimer). Ayurvedic formulations COVID-1 (Rafel), COVID-2 (Metonity), COVID-3 (Vikrant), Rudramrut syrup, Hemgarbh Pottali, Swaskas Chintamani Ras, and Suvarna Kalpa were administered with standard oxygen and supportive modern care. Results: Marked improvement in oxygen saturation (from 70% to 97%), reduction in LDH (692→487 IU/L), and radiological improvement were observed within 10–14 days. None of the patients required ventilatory support. No adverse events occurred. Conclusion: Ayurvedic management focusing on Dhatwagni Deepana, Strotoshodhana, Oja Vardhana, and Rasayana significantly improved respiratory and systemic function, showing potential in mitigating cytokine storm effects. Integration of Ayurveda in critical COVID-19 care can reduce mortality and post-COVID complications.

Keywords: COVID-19, Ayurveda, Cytokine storm, Dhatwagni Mandya, Rasavaha Strotas, Suvarna Kalpa.


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