Abstract

ANTIBACTERIAL ACTIVITY OF BENZIMIDAZOLE DERIVATIVES: A MINI REVIEW

*Vaishnavi S. Bawadkar, Dr. Megha T. Salve

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Abstract

Benzimidazole derivatives are widely significant due to their inclusion in various types of medicinal drugs, including anticancer, anticoagulants, antihypertensives, anti-inflammatory, antimicrobials, antiparasites, antivirals, antioxidants, immunomodulators, proton pump inhibitors, hormone modulators, CNS stimulants and depressants, lipid level modulators, antidiabetics, and others. This makes them an essential moiety in medicinal chemistry. Due to this significant importance, it draws the attention of researchers to create more effective benzimidazole derivatives for various biological activity screenings. There are numerous reviews and mini-reviews regarding the significance of the benzimidazole nucleus for medicinal purposes. The present study aims to review the antibacterial activity of compounds containing a benzimidazole nucleus separately, within the period from 2011 to 2017. This review will assist in the creation of effective benzimidazole derivatives.

Keywords: Benzimidazole; Medicinal drugs; Antibacterial activity; Synthesis.