Abstract

HERBAL COMPOUNDS AND THEIR MECHANISM IN WOUND MANAGEMENT

Siddesh Lande*, Dr. Karishma Nikose, Achal Mandale, Samiksha Thaware, Sanjiwani Pawar, Tejas Thlan

Abstract

The classical era, medicinal plants have already been employed as a resource for medicine and in the healing of wounds. Despite the use of standard medicines, chronic wounds are linked to significant healthcare and socioeconomic consequences. The mechanisms may result from the emergence of innovative wound-healing techniques utilizing medicinal plants in combination with nanotechnology. In this review, herbal formulations like biodegradable nanoparticles, films, fibers, hydrogels, and ointments with antibacterial, antioxidant, and anti-inflammatory characteristics are used in combination with herbal medicines to use in wound healing. Involved in skin healing. Commencement of a tissue lesion, a series of molecular and cellular actions take place to restore the injured tissue. This process is known as regeneration and tissue repair. Sequential events involving the integration of dynamic processes involving soluble mediators, blood cells, and parenchymal cells result in the exudative, proliferative, and extracellular matrix remodeling stages. The development of tissue edema is aided by exudative processes that happen after damage. By recruiting myofibroblasts and fibroplasia, the proliferative stage aims to decrease the area of tissue damage.

Keywords: Wounds healing; bandages; Hydrogels; Nanoparticles; Herbal Formulations; Aloe Vera.