Abstract

REVIEW ON TOBACCO AND ORAL SQUAMOUS CELL CARCINOMA ON MANAGEMENT/ CONTROL OF MOUTH CANCER

*Siddhi Bhor, Bhagyashri Hagare

Abstract

Oral Squamous Cell Carcinoma (OSCC) is one of the most common forms of mouth cancer, strongly associated with tobacco consumption in both smoking and smokeless forms. The uncontrolled growth of abnormal cells in the oral cavity not only damages local tissues but can also spread to distant organs through blood and lymphatic systems, leading to lifethreatening conditions. Tobacco use remains the most preventable cause of oral cancer, yet it continues to contribute significantly to cancer-related morbidity and mortality worldwide. This review focuses on the link between tobacco and OSCC, highlighting its pathogenesis, risk factors, and health burden.

Keywords: Tobacco and nicotine pharmacokinetics, Oral cancer epidemiology, Tobacco-induced carcinogenesis , Mouth cancer management.