Abstract

A CASE REPORT ON AUTOIMMUNE HEPATITIS

Jahnavi G.*, H. P. Sahana, Sumangala V. and Dr. RLN Murthy

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Abstract

Introduction: Autoimmune hepatitis is defined as rare disease of unknown etiology characterized by un-resolving inflammation of the liver with presence of interface hepatitis, hyper gamma globulinemia and auto antibodies. AIH age spectrum is broad, from small infants to adults>60 years old, it has been described in both sexes (more common in women), all races, and ethnicities. Case Presentation: A 29 years women admitted to the female medical ward of general medicine in tertiary care hospital, with the chief complaints of blackish discoloration of stools since one day which was foul smelly and watery and bleeding from nose one episode since the day of morning. Her past history revealed that she was a known case of autoimmune hepatitis-chronic liver disease on regular medication. On examination her BP was 80/50mm of Hg, Pulse rate was 90bpm and SPO2 was 95%@RA. External examination revealed the presence of icterus, hence physician advised for tests like Complete blood count, Liver function tests, Kidney function tests, Biochemistry, Serum electrolytes, Retic count, Peripheral smear only, Vitamin B12, Serum folic acid, HCV & HBS AG- Rapid, HIV I & II, Abdomen-Pelvic Sonography, MRI CHOLANGIOPANCREATICOGRAPHY, liver-LIA for IgG antibodies, LDH test, Upper GI Endoscopy, Sputum culture and sensitivity test, Ceruloplasmin, Immunoglobulin IgG serum test, Copper- 24hours urine test, Autoimmune serology panel, Anti-Nuclear Antibody test by Indirect Immunofluorescence Assay (IFA), ANA(Anti-Nuclear Antibody) Pattern Interpretation panel for the further diagnosis. Conclusion: Autoimmune hepatitis is a immunosuppressed disease and more likely to be affected to the patients of liver disease associated with immunodeficiency. Early diagnosis and preventive measures should be undertaken to prevent the development of disease.

Keywords: Human immunodeficiency virus (HIV), Lactate dehydrogenase (LDH), Hepatitis c virus (HCV), Antinuclear antibody (ANA).