Abstract

LIPOSOMES IN COSMECEUTICALS

Thorat Sakshi R., Kotkar Atiksha V., Fulsundar Apeksha S., Shelke Viraj B.

Abstract

Liposomes are microscopic, spherical vesicles created from phospholipid bilayers and are widely used in advanced skincare formulations to enhance the delivery of active cosmetic ingredients. Their structure resembles cell membranes, allowing them to encapsulate both water-soluble and oilsoluble substances within different compartments. This dualloading ability protects sensitive molecules from oxidation, UV degradation, and chemical instability. As a result, liposomebased products show improved stability, deeper penetration, and a controlled release of active compounds. Their role in cosmetics has increased significantly due to growing demand for products that deliver measurable skin benefits. Liposomes can carry a wide range of actives antioxidants, vitamins, peptides, botanical extracts, ceramides, growth factors, and whitening agents making them one of the most versatile nanocarrier systems in dermal formulations. Liposomes are versatile, biocompatible vesicles widely used in cosmeceutical formulations to enhance the delivery and performance of active ingredients. Composed of phospholipid bilayers, they encapsulate both hydrophilic and lipophilic compounds, improving their stability, penetration, and controlled release into deeper skin layers. In modern skincare, liposomes are employed to transport vitamins, antioxidants, peptides, botanical extracts, and anti-aging agents more efficiently than conventional systems. Their structural similarity to cell membranes allows better fusion with the stratum corneum, resulting in improved hydration, reduced irritation, and enhanced bioavailability of actives. Liposomal formulations also protect sensitive ingredients from degradation caused by light, oxygen, and enzymes. Overall, liposomes play a significant role in cosmeceuticals by increasing product efficacy, targeting specific skin concerns, and promoting safer, more effective dermal therapy. Liposomes are phospholipid-based vesicles widely used in cosmeceuticals to enhance the delivery and performance of active ingredients. Their bilayer structure allows encapsulation of both water-soluble and oil-soluble compounds, improving stability, penetration, and controlled release into the skin. Liposomes protect sensitive ingredients like vitamins, antioxidants, and botanical extracts from degradation and facilitate deeper absorption by merging with the skin’s lipid layers. This targeted delivery helps increase hydration, reduce irritation, and boost the overall effectiveness of skincare formulations. As a result, liposomes have become a key technology in cosmeceuticals, supporting advanced anti-aging, brightening, and skin-repair treatments.

Keywords: Liposomes, Biocompatible, Cosmeceuticals, Antioxidants, Nanocarrier, Bioavailability, U V Degradation, lipophilic.