Abstract

THERAPEUTIC POTENTIAL OF MADHUSARPI IN WOUND HEALING: A COMPREHENSIVE REVIEW

Dr. Pradeep Sariyam*, Dr. Aditya Nema*, Dr. Hari Prakash Sharma*

Abstract

Wound healing is a natural restorative response to tissue injury, and is complex process to achieve anatomical and functional integrity of disrupted tissue by various component like neutrophil, macrophages, lymphocytes, fibroblasts, collagen; in an organised staged pathway -Haemostasis →inflammation→ proliferation → matrix synthesis (collagen and proteoglycan ground (substance) maturation → remodelling → epithelialisation → wound contraction (by myofibroblasts).[1] Acharya sushruta, the father of surgery described in his text “Shashti Upakramas” for the management of wound (vrana) these are the 60 different regimens for the purpose of wound healing the cover all the aspect of wound healing. Madhusarpi is one of them which is indicating for Sadyovrana.[2] Madhusarpi is combination of Madhu (Honey) and Sarpi(Ghee) which is describe for sadyovrana mostly occurs due to trauma, surgical wound, accidental injuries etc.

Keywords: Madhusarpi, Sadhyovrana, vrana, wound healing, Honey, Ghee.