WJPR
World Journal of Pharmaceutical Research
( An ISO 9001:2015 Certified International Journal )
An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
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WJPR Citation
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| All | Since 2020 | |
| Citation | 8502 | 4519 |
| h-index | 30 | 23 |
| i10-index | 227 | 96 |
Best Article Awards
Best Paper Award : Dr. Dhrubo Jyoti Sen
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Abstract
IN VITRO EVALUATION OF THE ACTIVITY OF AQUEOUS EXTRACT OF A PLANT CODED PHYLLAM (PHYLLANTHUS AMARUS) ON TWO STRAINS OF MYCOBACTERUM TUBERCULOSIS AND ONE STRAIN OF MYCOBACTERUM ULCERANS
1Pharmacodynamics Biochemical Laboratory, UFR Biosciences, Felix Houphouet Boigny University. PO Box, 582, Abidjan 22- Côte d’Ivoire. 2Malariology Unit and Laboratory of CNR Chemoresitance, Pasteur Institute of Côte d’Ivoire, PO. BOX, 01 BP 490 Abidjan, 01 3Laboratory of Basic and Clinical Biochemistry, Pasteur Institute of Cote d’Ivoire.PO. Box, 01 BP 490 Abidjan 01 4Biochemical Laboratory, UFR medical Sciences, Felix Houphouet Boigny University. PO Box, 582, Abidjan 22- Côte d’Ivoire.
Abstract Burili ulcer and tuberculosis are diseases caused by mycobacteria and are a real public health problem in Côte d'Ivoire. We evaluated the activity of the aqueous extract of Phyllanthus amarus on the in vitro growth of two strains of M.tuberculosis (H37Rv and RF94) and one strain of M. ulcerans recorded under the name (02003). The results showed that all strains tested were susceptible to the aqueous extract of Phyllanthus amarus with minimum inhibitory concentrations (MIC) of 16 mg / ml for RF94 and 64 mg / ml for H37Rv and 02003 strains. This study shows that it is necessary to widen our research on more extracts tested in vitro and in vivo to enhance the bactericidal activity of Phyllanthus amarus. Keywords: [Full Text Article] [Download Certificate] |
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