Abstract

ESTIMATION OF BIOCHEMICAL PARAMETER OF HUMAN BREAST CARCINOMA IN DIFFERENT LOCALITIES AROUND CHENNAI CITY, TAMIL NADU.

Pushpa Rani.V*

Abstract

One hundred and eighty breast cancer subjects were considered and classified into three groups according to their age: 31-40, 41- 50 and 51- 60 years. They were clinically diagnosed at different hospitals located in an around Chennai City, Tamilnadu, India. Hematology analyzers provide accurate quantitative information about blood cells and can even identify specimens with abnormal cells. It was used for in vitro diagnostic use in clinical laboratories. The instrument employs a non-optical scanning system providing a counting rate in excess of six thousand individual cells per second with a counting interval of 15 seconds. All the biochemical parameters of total protein, Total cholesterol, HDL cholesterol, albumin, globulin, urea, bilirubin, triglycerides, low-density lipoprotein, very low-density lipoprotein, acid phosphatas, SGOT, alkaline phosphatase, SGPT, LDH were analyzed by using colorimetry. This study suggesting that there was a significant increase in total plasma, lipids, total cholesterol, LDL - cholesterol, VLDL, Phospholipids, triglycerides, free fatty acids in malignant breast cancer patients. The present study also revealed that this work is very useful for the diagnosis of a broad range of breast pathologies and as far as we are concerned, similar work had not been made in the literature.

Keywords: Carcinoma breast, Total protein, Total cholesterol, HDL Cholesterol, Albumin,Globulin, Urea, Bilirubin, triglycerides, low-density lipoprotein, Very low-density lipoprotein, Acid phosphatas , SGOT, Alkaline phosphatase, SGPT, LDH, Colorimetry.