Abstract

THE CONCEPT OF ANTIMICROBIAL ACTIVITY IN AYURVEDA AND EFFECT OF ARKADI GANA ON GRAM NEGATIVE BACTERIA

Dr.Premsukh*, Dr.Ashok kumar, Dr.Narinder Singh, Dr.P.Hemantha Kumar

Abstract

Purpose: To evaluate the concept of antimicrobial activity & gramnegative activity of the Arkadi gana. Introduction: In Ayurveda diseases are broadly classified into exogenous and endogenous based on etiological origin. Micro-organism exercises a major part among the exogenous categories. Microorganisms in the external environment have existed on earth for 3.5 billion years.It is quite natural that Ayurveda, the oldest health care system in the world, will not have the word 'Antibiotics'. Various types of diseases produce by these organisms and modes of spread are also described in Ayurveda like Kustha, Jvara, Sosa (consumption), Netrabhisyanda (conjunctivitis) and Opsargic roga (Infectious disease).The treatment of these disease are Rakshoghana Karma, Manidharna, Dhupan etc are prescribed in Ayurveda. Methods: For antimicrobial activity aqueous, ethanol (Rotatory shaker method) and petroleum ether extracts (Soxhlet Apparatus) were prepared as per API guidelines and tested on different species of common pathogenic bacteria that’s responsible for wound infection. Anti microbial study was done by 12 samples against 4 bacteria. In vitro studies were undertaken to assess the antibacterial activity at Institute of biomedical and Industrial research, jaipur. RESULTS: Disc diffusion method was employed and zone of inhibition are measured. Results are analyzed statistically, with one way anova and dunnett's multiple comparisons test are applied. Discussion & Conclusion: Arkadi gana are strong antibacterial agent against all bacteria, these pathogens are responsible for wound infections, osteomyelitis and associated with dysentery, diarrhoea, gastroenteritis, urinary tract infection and skin infections (impetigo, folliculitis).

Keywords: Arkadi gana, antimicrobial activity, Ayurveda.