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WJPR

World Journal of Pharmaceutical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

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Abstract

EFFECT OF IPOMEA OBSCURA LINN IN NEPHROTOXIC INDUCED IN EXPERIMENTAL RATS

V.Elango* and D.Eazhisai Vallabi

Abstract

The present study has been undertaken to evaluate with the nephroprotective effect of crude powder of Ipomea obscura Linn leaves in normal and gentamicin induced nephrotoxic rats. Gentamicin was used to induce nephrotoxicity in male albino rats weighing between 100-120gms for 30 days. Effects of the plant crude powder treatment on the hematological and renal histological profile in gentamicin nephrotoxic rats were also evaluated. Ipomea obscura used in Siddha system of medicine and the plant is known to contain various active principles of therapeutic value and to possess biological activity against a number of diseases.

Keywords: Renal failure, Albino rats, Ipomea obscura L, Urea, Uric acid, Creatinine, phosphatases and transaminases and Cystatin C.

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