Abstract

EFFECT OF GRAM NEGATIVE BACTERIA INFECTION ON RENAL AND LIVER FUNCTION

Rajeswari S, Tasneem Banu, Anila Mathan and Swaminathan S*

Abstract

In a tropical country like India, particularly in Tamilnadu, infection by gram negative bacteria is quite common and the four commonly infecting gram negative bacterias are Klebsiella, Pseudomonas, Enterobacter and Escherichia coli. Numerous studies done previously have indicated that infections by gram negative bacteria affects all vital organs, particularly liver and kidney. The aim of this study was to find out the effect of gram negative bacteria on renal and liver functions. This study was carried out with a reasonable number of patients (total 67) involving both sexes in each type of infection. Our aim was to find out the effect of infection by gram negative bacteria on renal and liver functions. It has been shown that both the organs are affected during such infections as per alterations observed in the biochemical analytes associated with the organs. While Klebsiella, Ecoli and Enterobacter affect both liver and renal functions, Pseudomonas affect only liver functions as per statistical analysis presented in this paper.

Keywords: Klebsiella, Pseudomonas, Enterobacter, Escherichia Coli, Urea, Creatinine, ALT.