Abstract

NOVEL DRUG DELIVERY SYSTEM BASED FAST DISSOLVING ORAL FILMS: A DETAIL REVIEW ARTICLE

*Atharva Ajit Kolbe, Satyam Narayan Kumbhar, Saniya Amin Jamadar, Silvie Gonsalvis, Dr. Manoj Kadam, Mr. Pawar Rahul

Abstract

Fast-dissolving orally disintegrating films are designed to rapidly dissolve when they meet a moist surface or fluids such as saliva, typically within a few seconds. Unlike tablets, capsules, or oral liquids, they do not require the use of additional liquids like water. This makes them a highly convenient dosage form for patients and provides significant marketing benefits. In paediatric, geriatric populations, and in patients who experience a fear of choking, orally disintegrating films are considered a more convenient and widely accepted dosage form. The obtained results indicate that the formulated oral film could serve as an innovative dosage form for enhancing drug delivery and achieving a faster onset of action, while also improving patient compliance. The term “Oro dispersible” refers to dosage forms that rapidly disperse within the oral cavity. The disintegration time for such formulations should generally not exceed 3 minutes. These dosage forms are commonly available as tablets and mouth dissolving films, which release the drug immediately after placement in the mouth, resulting in a rapid therapeutic effect.

Keywords: Oral films, swallow, Fast dissolving, Rapid, Oral mucosa.