Abstract

MICROEMULSION: A NOVEL DRUG CARRIER APPROACH

*Shish Kumar, Shardul Chauhan, Ankit Kumar Pandey, Shashank Patel, Anurag Goel

Abstract

Microemulsions are liquid mixtures of water, oil, and surfactant that are isotropic transparent, and thermodynamically steady often in combination with a co-surfactant. The "oil" might be a complex blend of different olefins and hydrocarbons, while salts and other materials could be present in the aqueous phase. Microemulsions create by merely mixing the components, in contrast to conventional oils, that required severe shear conditions to produce. Furthermore, the droplet size in these microemulsions is consistent, falling between 100 and 1000 A (10 and 100 nm), and the oil/water interfacial tension is remarkably low. Nowadays, the use of microemulsion in a variety of technological applications is a rapidly expanding business with global relevance. Since the droplet size of microemulsions is less than 25% of the wavelength of visible light, they are transparent. This article attempts to illustrate the importance of microemulsions as DD Vehicles by giving a general review of their creation, characterization, and use in different drug delivery routes.

Keywords: Microemulsion, Surfactants, Co-surfactants, Bioavailability.