Abstract

FORMULATION AND EVALUATION OF WOUND HEALING GEL FROM BULRUSH AND NEEM

Swamini Balu Dukare*, Akshay Fulsundar, Chavan Rutuja Sunil, Vishakha Vishwanath Dongare, Vedika Vijay Gadge

Abstract

Inflammation, tissue development, and skin remodeling are all part of the intricate biological process of wound healing. Because of their antibacterial, anti-inflammatory, and healing qualities, herbal remedies are frequently used to treat wounds. The goal of this study is to create and assess a herbal wound healing gel that contains extracts of Azadirachta indica (neem) and Typha angustifolia (bulrush). Appropriate gelling agents will be used to make the gel, and its pH, viscosity, spreadability, homogeneity, and stability will all be assessed. Additionally, the gel's ability to heal wounds will be investigated. Because of their increased patient compliance, safety, and efficacy, herbal formulations are becoming more and more popular. Flavonoids, tannins, and phenolic compounds are among the active components found in the chosen plants that aid in the production of collagen, lower inflammation, and ward off microbial infection. Neem has potent antibacterial and antiseptic qualities, while bulrush has antioxidant and tissue healing activities. By creating a moist environment for the wound, the gel dosage form speeds up healing and lessens the production of scars. The goal of this research is to create a topical herbal wound healing gel that is stable, safe, and efficacious.

Keywords: Bulrush, Neem, Herbal Gel, Wound Healing, Extraction.