Abstract

IN VIVO EVALUATION OF THE ANTI-ALZHEIMER’S POTENTIAL OF THE ETHANOLIC EXTRACT OF ARTOCARPUS HETEROPHYLLUS SEEDS IN SCOPALAMINE- INDUCED MALE ALBINO RATS

B. Soujanya, M. Nagaraju, N. Santhosh Kumar, P. Pravalika, V. Deepika, Mrs. M. Jhansi Rani*, Dr. Chandra Sekhar Rao Baru

Abstract

Alzheimer's disease (AD) is a chronic, progressive neurodegenerative disorder and the leading cause of dementia worldwide. It is characterized by progressive deterioration of memory, cognition, language, executive function, and behavior, ultimately affecting activities of daily living. The increasing life expectancy of the global population has led to a rapid rise in the prevalence of AD, making it a major public health challenge with substantial social and economic impact.

Keywords: Alzheimer's disease; Artocarpus heterophyllus; Scopolamine; Memantine; Neuroprotection; Cognitive impairment; Phytochemicals.