Abstract

INVITRO ANTILITHIATIC ACTIVITY OF ALCOHOLIC LEAF EXTRACT OF AGERATUM CONYZOIDES LINN.

Tailor Chandra Shekhar*¹, Goyal Anju²

Abstract

Herbal medicine is a natural remedy for all the disease. The herbal medicines do not have any side effect and it is cost effective and safest medicine from an ancient periods. Urolithiasis is a very painful disease that has afflicted a wide sector of human population since ancient times. Calcium-containing stones are the most common comprising about 75% of all urinary calculi, which may be in the form of pure calcium oxalate (50%) or calcium phosphate (5%) and a mixture of both (45%). In this study ethanolic and aqueous extracts of both leaves and roots of Ageratum conyzoides Linn. plant were evaluated for their potential to dissolve experimentally prepared kidney stones calcium oxalate and calcium phosphate, by an invitro model. Out of which only ethanolic leaves extract of this plant produced highest dissolution of both stones when compared to standard drug cystone and other extracts at 10mg. concentration. However, it was more effective in dissolving calcium oxalate stones than phosphates. Reference drug formulation cystone was found to be more effective when compare to all other test extracts.

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