Abstract

MOLECULAR IDENTIFICATION AND DOCKING ANALYSIS OF MARINE BACTERIA (Bacillus flexus)

Manikandaprabhu S*, Senthilraja P, Manju J, and Prakash M.

Abstract

Mangroves are growing in extreme conditions of the marine environment and the microorganisms present in the environment have to be highly tolerant of the extreme conditions. Therefore, we expected that the microorganisms from mangrove soil may be the potential source of bioactive compounds. We aimed to investigate the Bacillus flexus from mangrove soil, analyze the morphology, cultural and genotypic identification by using 16S rRNA technique. In addition to identify the novel compound by (GC-MS) Gas Chromatography Mass Spectrum from mangrove soil. The identified potential bioactive compounds were docked against breast cancer responsible pathway protein.

Keywords: Bacillus flexus, 16S rRNA, GC-MS, Phylogenetic tree, Breast cancer, Mangrove soil.