Abstract

BIOACTIVITY OF Myristica fragrans METHANOL EXTRACT

Pritha Chakraborty, Lavanya P. and Jayanthi Abraham*

Abstract

Objectives: Myristica fragrans, commonly called nutmeg, is an aromatic evergreen tree. It has been found to possess medical value and has been used to treat rheumatism and stomach complaints in Indonesia, Malaysia, England, and China, because of its essential oil. However, the effect of Myristica fragrans methanol extracts on the area of cytotoxicity is unexplored, hence the present work was aimed at evaluating the effect of extracts on cancer cell line and also on clinical pathogens. Methods: Phytochemical and analytical studies (TLC and GC-MS) was evaluated with methanol extract of Myristica fragrans. Antimicrobial activity of Myristica fragrans was also checked against nine clinical pathogens. Antioxidant and anticancer study against MG 63 cell line was also carried out. Result: Results has shown that Myristica fragrans extract posses antimicrobial activity against both Gram positive and Gram negative organisms and moderate antioxidant and anticancer activity. Conclusion: The present support the fact that Myristica fragrans extract can be used as future drug.

Keywords: Nutmeg, Phytochemical studies, Analytical studies, Clinical pathogens, MG 63 cell line.