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Abstract

ANTI-ACNE SYNERGISTIC HERBAL FACE WASH GEL: FORMULATION, EVALUATION AND STABILITY STUDIES

Harsharan Pal Singh*, Neeraj Samnhotra, Sumeet Gullaiya, Ishpreet Kaur

Abstract

Acne is a chronic inflammatory disorder of pilocebaceous unit, which involves increased sebum production by sebaceous glands and abnormal desquamation of hair follicles occur in response to increasing androgen levels with the onset of puberty. Obstruction of follicles causes follicular distention which is often accompanied by the proliferation of the bacteria Propionibacterium acnes and the activation of an inflammatory response. The Aim of this study was to formulate and evaluate the herbal face wash gel containing extracts of Azadirachta indica (Neem), Curcuma longa (Haldi), Coriandrum sativum (Dhaniya), Aloe berbadandis (Aloe Vera), Citrus limon (Lemon) and Mentha (Pudina) distillate using Carbomer Ultrez 20. The plants have been reported in the literature having good anti-microbial, anti-oxidant and anti-inflammatory activity. Prepared formulation was evaluated for various parameters like colour, appearance, consistency, pH, viscosity, stability studies and consumer acceptance test.

Keywords: Acne vulgaris, Anti-acne activity, Anti-microbial, Inflammatory response, Traditional herbs.


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