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Dr. Dhrubo Jyoti Sen
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Abstract

INCIDENCE OF LUTEINIZED UNRUPTURED FOLLICLE IN CONTROLLED OVARIAN STIMULATION USING RECOMBINANT AND URINARY HCG AS OVULATION TRIGGER AND STUDY OF ITS VARIOUS OUTCOMES.

Dr. Mohit R Saraogi*, Dr. Amit A Patankar, Dr. Leena A Patankar

Abstract

Objective: 1. To study and compare the incidence of luteinized unruptured follicle in controlled ovarian stimulation using urinary HCG and recombinant HCG as ovulation trigger. 2. To study recurrence rate of Luteinized unruptured follicle. 3. To study pregnancy and miscarriage rates in women with luteinized unruptured follicles. 4. To look for additional predisposing factors other than commonly known ones which may predispose to luteinized unruptured follicles. Design: A retrospective study Setting: An institute based study. Patients : 1217 women who fit the inclusion criteria were subject to controlled ovarian stimulation and were given ovulation trigger using either recombinant HCG (569 women) or Urinary HCG ( 648 women). The women were further evaluated for incidence of luteinized unruptured follicle and subsequent outcomes. Results: 1. The incidence of luteinized unruptured follicle was 3.54% with urinary HCG and 4.04% with recombinant HCG as ovulation trigger. This was statistically insignificant. 2. The recurrence rate of luteinized unruptured follicle was 63.88% in our study. 3. Patients with PCOS had a high predisposition to develop Luteinized unruptured follicles. 4. The pregnancy rate in women with luteinized unruptured follicle was 4.3% with a 50% miscarriage rate and this was independent of other predisposing factors for LUF.

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