Abstract

THE EFFICACY OF ALOEVERA EXTRACT ON LIVER CARBOHYDRATE METABOLIC PROFILES IN ALLOXAN INDUCED DIABETIC MALE ALBINO-RATS

Ravi Naik Mude*

Abstract

Aloe vera has been mentioned in Indian System of traditional medicine to be of value in the treatment of many diseases. The present study was undertaken to asseses the effect of Aloe vera on the Carbohydrate metabolic profiles in Alloxan induced diabetic rats. Aloe vera leaf get extract administered orally to different groups of rat at a dose of 300 mg/kg body weight. Four groups (n=6) follows, control rats, control + Aloe vera, diabetic rats (Alloxan 40mg/kg body weight), diabetic + Aloe vera. The parameters studied are total carbohydrates, glycogen and glucose. These metabolic profiles were decreased in diabetic rats and glucose increased. Whereas, with Aloe vera extract treatment in diabetic rats these carbohydrate metabolic profiles were increased and glucose decreased. The observed reductions in carbohydrate metabolic profiles during diabetic condition in liver tissue may be due to the alterations in the Carbohydrate metabolism. In conclusion the Aloe vera extract posses hypoglycemic property in diabetic rats, carbohydrate metabolic profiles were came to normalcy.

Keywords: Diabetes, Aloe vera, Alloxan, liver, Carbohydrates metabolic profiles.