Abstract

REGULATION OF TYPE-II DIABETES TREATMENT WITH ALOE VERA EXTRACT ON LIPID METABOLISM STATUS IN LIVER ALLOXAN INDUCED MALE RATS

Ravi Naik Mude*

Abstract

To investigate the protective use of ethanolic extract of Aloe vera on cholesterol, lipid peroxidation, Triglycerides levels in diabetic male Albino-rats. The protective effect of Aloe vera in Experimental was evaluated in this study. Three months old male wistar rats were divided into 4 groups (n=6) namely: Control, Control + Aloe vera (300 mg/ kg body weight), diabetic (Alloxan 40 mg/kg body weight), (diabetic + Aloe vera (300 mg/kg body weight) the experimental period was 21 days. In the present study the work was undertaken to evaluate the potential anti hyper lipid anemic effect of Aloe vera leaf extract in liver tissue of Alloxan induced diabetes rats. The levels of cholesterol, lipid peroxidation, Triglycerides in liver tissue were increased significantly in diabetic rats. In case of, Diabetic + Aloe vera leaf extract to present the development alteration in lipid metabolism status in liver tissue maintained near normal while comparing with non diabetic rats.

Keywords: Diabetes, Aloe vera, Alloxan, Lipid metabolism, Rats.