Abstract

STUDY OF INCREASED ANTIPHOSPHOLIPID ANTIBODIES WITH INCREASED ANTI RUBELLA ANTIBODIES IN PREGNANT WOMEN IN BAGHDAD CITY

Dr. Ali A. Mahdi, Dr. Amal A. Kareem, Dr. Nihad Kh. Tektook*, Dr. Leeqa H.Mahde

Abstract

Back ground: Many infections which founded with antiphospholipid antibodies (aPL), so a major cause of pregnancy complications and recurrent miscarriages if no found other causes, as well as rubella causing this complication and abortion. Subjects and methods: To investigate the relevance of Antiphospholipid antibodies with Anti Rubella antibodies in pregnant women in Baghdad city, by collected 176 sera from January to July -2015 from pregnant women with and without abortion in Baghdad hospital, and determine aPL and Rubella antibodies by enzyme linked immunosorbent assay (ELISA). Results: the results revealed high percentage 80.9% of apL with abortion in pregnant women infected with Rubella viruse, while 13.8% aPL negative (-ve) without abortion, 5.3% apL (-ve) with abortion, so results represent a relation between apL and abortion in Rubella infected pregnant women, as well as low percentage (13.3%) of apL (+) with abortion in non-infected pregnant women with Rubella viruse, while high percentage (73.9) appeared with non-Rubella infected pregnancy with apL (-ve), but (13.3%) abortion with apL (+) in control. Conclusion: Antiphospholipid antibodies high correlated with increased Anti Rubella antibodies in pregnant women but low relation between of apL with abortion in non-infected pregnant women with Rubella viruse in Baghdad city.

Keywords: apL (Antiphospholipid antibodies), Rubella, Pregnancy, abortion.