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WJPR

World Journal of Pharmaceutical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

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Abstract

SYNTHESIS OF NEW SCHIFFâ€™S BASSES 4-CHLORO COUMARIN DERIVATIVES

Redha I. AL-Bayati, *Shakeeb M. Hameed, and Hiba H. Ibraheem

Abstract

This work included synthesis of several new Schiff bases by condensation of 4- Chloro-3-formylcoumarin[1] and appropriate aromatic amine (Aniline, p-Toluidine, p-Aminoacetophenone, p- Aminobenzoate, p-Aminophenol, m-Aminophenol, m-Toluidine and m-Aminoacetophenone) to obtain Schiff bases[2-9] and with Hydrazidecoumarin Derivatives (3- hydrazidecoumarin[10] 5- Bromo- 3- hydrazidecoumarin [11]) to obtain Schiff bases[12,13] The new compounds were characterized by using of Melting point and FT-IR spectroscopy, and some of them by 1H-NMR spectrum.

Keywords: Schiff bases, 4-Hydroxycoumarin.

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