Abstract

EFFICIENCY OF LENTINUS EDODES ON ENTAMOEBA HISTOLYTICA IN LABORATORY MICE

Dr. Israa Mohammad Abd AL-Khaliq* and Dr. Rusol, M. Al-Bahrani

Abstract

The principal objective for this study was to evaluate the efficacy of Lentinus edodes against Entamoeba histolytica infection compared with metronidazole by using mice models. A single oral dose of Lentinus edodes water extracts of up to (0.1ml ∕mice∕day) reduced parasite appearance in feces and disappear completely atthe (8th) day compared with metronidazole the cysts parasite continued till (10th) day. The histomorphological study findings showed in the group which was given Lentinus edodes the majority of tissue intestine return to normal shape. These finding indicated that Lentinus edodes may be effective in treating Entamoeba histolytica.

Keywords: Entamoeba histolytica, Lentinus edodes, aqueous extract, metronidazole, intestinal tissue.