Abstract

POTENTIAL ACTIVITIES OF ISOXAZOLE DERIVATIVES

Angirekula Naga Jyothi*, Jonnakuti Poojitha, Gollapalli Naga Raju, Rama Rao Nadendla

Abstract

Isoxazole derivatives constitute an important class of heterocycles in drug discovery. They are clinically effective as antibacterial, antifungal, anti-inflammatory, anticancer, anti-tubercular and antineoplastic agnts. Modification in their structure has offered a high degree of diversity that has proven euseful for the development of new therapeutic agents having improved potency and lesser toxicity. Considering the extensive research on isoxazolein the past, it was essential to review the wide spectrum of biological activity of isoxazole. To conclude, this review will be beneficial for new drug discovery of isoxazolemoiety.

Keywords: Isoxazole, Analgesic, Anticancer, Antimicrobial, Anticonvulsant.