WJPR Citation New

  All Since 2019
 Citation  7475  4312
 h-index  28  21
 i10-index  197  83

Login

Best Paper Awards

World Journal of Pharmaceutical Research (WJPR) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.
Best Paper Award :
Dr. Dhrubo Jyoti Sen
Download Article: Click Here

Search

Track Your Article

Abstract

PREFORMULATION AND FORMULATION STUDY OF ANTICANCER PRINCIPLE OF PIPERINE

*Sanjay Kumar Chelak

Abstract

Piperine increases bioavailability of many drugs and nutrients by inhibiting various metabolising enzymes. Piper nigrum L and its active constituent ‘’Piperine’’ exhibits diverse pharmacological activities like antihypertensive, antiplatelet, antioxidant, antitumor, anti-asthmatics, analgesic, anti-inflammatory, anti-diarrheal, antispasmodic, antidepressants, immuno-modulatory, anticonvulsant, anti-thyroids, antibacterial, antifungal, hepato-protective, insecticidal and larvicidal activities etc. Piperine's bioavailability-enhancing property may be attributed to increased absorption, which may be due to alteration in membrane lipid dynamics and change in the conformation of enzymes in the intestine. The approach is novel as the abundantly available natural product piperine is utilized as precursor for the synthesis of new potential anticancer agents. This review article concludes the bioavailability enhancing property, Preformulation and formulation study and anticancer property of piperine.

Keywords: Piperine, Anticancer, Liposomes, Preformulation, Bio-enhancer, Bioavailibity.


[Full Text Article]  [Download Certificate]

Call for Paper

World Journal of Pharmaceutical Research (WJPR)
Read More

Email & SMS Alert

World Journal of Pharmaceutical Research (WJPR)
Read More

Article Statistics

World Journal of Pharmaceutical Research (WJPR)
Read More

Online Submission

World Journal of Pharmaceutical Research (WJPR)
Read More