Abstract

CHEMICAL STUDY OF FATTY ACIDS IN MIMUSOPS ELENGISEEDS BY GC-MS AND COMPARISON OF ITS ANTIBACTERIAL ACTIVITY WITH TRIMETHOPRIM

*Raghuwanshi Jitendra, Rai Sonu, Shukla Rudra Narayan

Abstract

The aim of this study was to analyze the chemical and phytochemical composition of Mimusops elengi seeds. The individual constituents were identified by GC-MS method. In the analysis 11 components were identified which include-Pentadecanoic acid 14-methyl- methyl ester, Hexadecanoic acid ethyl ester, 10-Octadecenoic acid methyl ester, (E)-9-Octadecenoic acid ethyl ester, Methyl 9-eicosenoate, Methyl 19-methyl-eicosanoate, Hexadecanoic acid3- [(trimethylsilyl)oxy]propyl ester, Docosanoic acid ethyl ester, Hexadecanoic acid 3-[(trimethylsilyl)oxy]propyl ester, Docosanoic acid ethyl ester, Hydrocinnamic acid o-[(1,2,3,4-tetrahydro-2- naphthyl)methyl]-, Ethyl 14-methyl-hexadecanoate, 9-Octadecenoic acid (Z)- 2-hydroxy-1-(hydroxymethyl)ethyl ester. The phytochemical analysis of ethyl acetate extract shows presence of alkaloids, glycosides, tannins, saponins, & flavonoids. Quantitative analysis of magnesium, calcium, iron, copper shows presence of these minerals in the sample. The antimicrobial activity of M. Elengi seed extract when compared with Synthetic drug Trimethoprim shows that it exhibits good antibacterial properties and can be used for therapeutic purpose in future.

Keywords: Mimusops Elengi Linn., Ethyl acetate seed extract, antimicrobial property, composition Trimethoprim, UV spectrophotometry, GC-MS.