WJPR Citation New

  All Since 2019
 Citation  7475  4312
 h-index  28  21
 i10-index  197  83

Login

Best Paper Awards

World Journal of Pharmaceutical Research (WJPR) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.
Best Paper Award :
Dr. Dhrubo Jyoti Sen
Download Article: Click Here

Search

Track Your Article

Abstract

ANTI-ULCEROGENIC EFFECTS OF NIGELLA SATIVA L. MELANIN

Adila El-Obeid*, Kamal Eldin. H. ELTahir, Hamid Elhag, Adil M. Haseeb

Abstract

Aim: The current study is to examine the effect of a Herbal Melanin (HM), obtained from the seed coats of Nigella sativa L., as antiulcerogenic agent against alcohol-, indomethacin-, aspirin-, stress- and combined stress and aspirin-induced gastric ulcers in rats. Method: Using Wistar rats, gastric ulcers have been induced by administration of alcohol-, indomethacin-, aspirin-, stress and combined stress and aspirin. Herbal melanin was administrated before or together with the ulcerogenic agents. Results: Pretreatment or co-administration of HM with the ulcerogenic agents at doses of 0.12 or 1g kg-1 body weight, by gavage, significantly protected the stomach against inducible ulcers. Conclusion: Our findings suggest that HM, extracted from the seed coats of Nigella sativa L, strongly protects from ulcers induced by alcohol, indomethacin, stress, or the combined ulcerogenic action of both stress and aspirin.

Keywords: Herbal melanin; Experimental ulcers; alcohol; indomethacin; aspirin; stress.


[Full Text Article]  [Download Certificate]

Call for Paper

World Journal of Pharmaceutical Research (WJPR)
Read More

Email & SMS Alert

World Journal of Pharmaceutical Research (WJPR)
Read More

Article Statistics

World Journal of Pharmaceutical Research (WJPR)
Read More

Online Submission

World Journal of Pharmaceutical Research (WJPR)
Read More