Abstract

TREATMENT OF BACTERIA CAUSING BURN WOUND INFECTIONS BY LACTOBACILLUS REUTERI AS A PROBIOTIC

Mustafa Attiyah Hadid*, Abdulwahid B. Al-Shaibani and Sadeq Abbas Al-Mukhtar

Abstract

study aimed to investigate the effect of Lactobacillus reuteri on pathogenic bacteria isolated from burn wound infections. A total of 51 swabs were obtained from patients of both sexes who admitted to Al- Kindy Teaching Hospital suffering from invasive burn wound infections for the period of November2014 to February 2015.The most common detected pathogenic species were Pseudomonas aeruginosa(43.7%) followed by Staphylococcus aureus (18.7%), Klebsiella pneumoniae (15.6%), coagulase-negative Staphylococci (9.3%), E. coli (4.6%), and each of Ps. putida, Ps. alcaligenes, Enterobacter cloacae, Acinetobacter baumannii, and Stenotrophomonas maltophilia (1.5%). Antibiotic susceptibility of isolates towards 10 commonly used antibiotics showed that all isolates were sensitive to Amikacin and Imipenem except of Stenotrophomonas maltophilia which was resistance to Imipenem. Adversely, all isolates were resistant to the penicillin group with the exception of coagulase-negative Staphylococci which were moderately sensitive to Ampicillin. When used as a probiotic, Lactobacillus reuteri excreted antibacterial activity against the burn wound infections bacteria. The maximum inhibition zone caused by Lb.reuteri concentrated filtrate was achieved against Ps. aeruginosa1 when it reached 18 mm followed by S. aureus17.2, while the minimum inhibition zone (7 mm) was against Acinetobacter baumannii.

Keywords: Burn wound infections, Lactobacillus reuteri, Probiotic.