Abstract

TOMATO EXTRACT AS AN ANTI-HYPERTENSIVE AGENT TO MODULATE BLOOD PRESSURE

Rasika R. Nikhade*, Mahesh A. Hadke and Suchita G. Waghmare

Abstract

Hypertension is the leading cause of cardiovascular disease. Tomatoes can make people healthier and decrease the risk of conditions such as cancer, osteoporosis and cardiovascular disease. Taking tomatoes and tomato products could reduce the risk of cardiovascular diseases because of lycopene in it. Red ripened tomato is a powerful antioxidant, Vitamin E and lycopene in tomato prevents LDL oxidation effectively. Tomatoes contain a great deal of Vitamin A and Vitamin C. Tomatoes are rich in potassium, which is known to reduce blood pressure. Lycopene extract from tomatoes is obtained by ethyl acetate extraction of the pulp of ripe red tomatoes. Provided herein is technology related to compositions and uses related to anti-hypertensive agents in tomatoes. Essential hypertension can be treated with one of several types of medications, including diuretics, β-adrenoreceptor blockers, inhibitors of angiotensin converting enzyme, calcium channel blockers, vasodilators and centrally acting agents. Vitamin C has effectively resulted in proper dilation of blood vessels in the cases of congestive heart failure, high cholesterol, angina pectoris and high blood pressure. It was discovered that sugar free tomato extracts exhibits an ability to reduce ACE activity.

Keywords: Hypertension, Tomato, Lycopene, Antioxidant.