Abstract

SYNTHESES CHARACTERIZATION AND BIOLOGICAL ACTIVITY OF MIXED LIGAND BASED METAL COMPLEXES OF 3D SERIES WITH 2,3-DIHYDROXYPYRIDINE(DHP) AND AMINO ACIDS GLYCINE(GLY), ALANINE(ALA), VALINE(VAL) AND LEUCINE(LEU)

Upendra Dhusiya, Seema Gautam, Sulekh Chandra* and Swati Agrawal

Abstract

Mixed ligand metal complexes of Mn(II), Fe(II), Co(II) and Cu(II) with 2,3-dihydroxypyridine (DHP) and amino acids glycine(gly), alanine(ala), valine(val) and leucine(leu) have been synthesized. Chemical and structural composition of all synthesized complexes were characterized by analytical and spectral studies i.e. elemental analysis, magnetic moment, electronic, IR and EPR spectral studies. On the basis of characterization data Mn(II), Fe(II), Co(II) complexes possessed octahedral geometry while Cu(II) complexes possessed tetrahedral geometry. The in vitro biological activity of the complexes was examined against the bacteria and fungus.

Keywords: Mixed ligand; amino acid; complex; IR; octahedral; tetrahedral; biological activity.