IMMOBILIZATION OF ADHATODA VASICA LEAF CELLS FOR ENHANCED PRODUCTION OF VASICINE
Chauhan Pradeep*, Panigrahi Mahendra
Abstract
Traditional techniques of callus and suspension culture do not fully
explore the range possibilities of cultured cells. Immobilization is the
advanced novel biotechnological approach, through which it is
possible to achieve a physiological state conducive for metabolite
production that may not have been attended otherwise. Vasicine is the
major alkaloid found in Adhatoda vasica, has been used for the
treatment of various diseases and disorders particularly of respiratory
tract. Leaf cell homogenate was immobilized in calcium alginate and
the effect of immobilization on cell growth, cell viability and cells
biosynthetic activity was observed.
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