Abstract

THE SEVERITY OF 5-FLUOROURACIL INDUCED GASTROINTESTINAL (GI) MUCOSITIS IT’S IMPACT ON TREATMENT.

Almokashfy Fa. I. A., Shayoub M. E.L.*, Ahmed M. El. Ali, M. AL Ab. Nihal, Abdalla Orsad, Ornasir Alya Almahadi, Asma Noureldaim Mahmoud Mohamed, Shadad S. A. and Hisham Mohamed Osman

Abstract

This study attempts to throw some light on the severity of gastrointestinal mucositis among cancer patients on chemotherapy. Number of 120 cancer patients, who were on chemotherapy (5fluorouracil) attending Radiation and Isotope Center in Khartoum was enrolled. A questionnaire results showed the patients were developed diarrheal toxicity revealing that, most patients were in grade (1) 79.8%, while only about 9% of them were having, grade (2), grade (3) and grade (4) approximately had equal distribution representing 5.6%. Four patients developed oral mucositis had equal distribution representing 50% in grade1 and grade2.

Keywords: severity, gastrointestinal mucositis, oral mucositis, cancer patients, 5fluorouracil