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WJPR

World Journal of Pharmaceutical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

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Abstract

GREEN SYNTHESIS AND CHARACTRISATION OF NOVEL TRIAZOLES DERIVATIVES OF 2-MERCAPTOBENZOTHIAZOLE

Mathapati Sushil Ramakant*, Vhadlure Amit Nillappa, Kalalawe Virbhadra Gangadhar, Swami Mantosh Bhimashankar, Ghuge Hanumant Gunaji, Dawle Jairaj. Kishanrao

Abstract

Novel 2-Mercaptobenzothiazole deriveties synthesized from 2- Mercaptobenzothiazole reacted with ethyl chloroacetate to get ester derivatives (3) using Green method. These ester converted to hydrazids (4) by reaction with hydrazine hydrate under MWI. 5- substituted 1,3,4-oxadiazole (5a-g) synthesized from hydrazide, substituted benzoic acid and phosphprous oxochloried by Microwave irradiation as reported in literature.1,3,4- Triazoles 6a-g synthesized from above oxadiazole 5a-g. The structure of newly synthesized compound was established by physico-chemical and spectral data analysis.

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