Abstract

ARTIFICIAL BLOOD SUBSTITUTES: A LIFE SAVING TOOL

Nandita Yadav, Ismat Fatima Rizvi, Mohd. Haris Siddiqui, and Alvina Farooqui*

Abstract

Blood is a specialized fluid of body that delivers necessary substances such as nutrients and oxygen to the body cells and transports waste products away from those cells. Artificial blood is a product that can act as substitutes of blood and can transport oxygen (oxygen therapeutics) and carbon dioxide throughout the body. Artificial blood will also lessen the demand for human blood supplies and give immediate response without triggering a rejection in cases of massive blood loss. They do not require any blood typing, so that they can be infused immediately and is applicable for all blood types patient. It can be produced by different methods such as synthetic production, chemical isolation, or by using recombinant biochemical technology. One basic approach to make an oxygen therapeutic is using Perfluorocarbons a chemical compound which can carry and release oxygen which maintain the circulating blood volume as well as the need of the patients.

Keywords: Human Blood, Artificial blood, Blood substitutes, oxygen therapeutics, Perflurocarbons