Abstract

AN IN-VITRO STUDY ON ANTIBACTERIAL ACTIVITY OF MIMOSA PUDICA, CYNODONDACTYLON AND IMPATIENS BALSAMINA

Seema Kamble, SushmaNadgoudar, Nayana Deshapande, Varsha Jayakar, Keshata Gaikwad, Ambarish Sindagi, Anmol Kurthkoti, Archana Kulkarni, Sadashiv S. O., Chandrashekhar Unakal

Abstract

Medicinal plants are nature’s gift to human to make disease free healthy life. Infectious diseases continue to represent a significant challenge to human medicine. The present investigation evaluates antibacterial activity of Mimosa pudica, Cynodondactylon and Impatiens balsamina. They were tested against gram negative bacteria such as Escherichia coli,Pseudomonas aeruginosa and gram positive bacteria such as Bacillus subtilis using agar well diffusion method using acetone and aqueous solvent extracts. The susceptibility of the microbes to the extract of the plants was compared with standard antibiotics tetracyline and azithromycin (30mcg/ml) as a positive control. The results revealed that alcoholic extracts of Mimosa pudica and acetone extracts of Impatiens balsamina showed very high antibacterial activity (16-19mm) against three pathogens at low concentration 10μl, while Cynodondactylon plant extract exhibited moderate zone of inhibition (10-12mm) at the same concentration. The acetone and alcohol extracts of three medicinal showed more effective zone of inhibition against both gram negative and gram positive bacteria. The present findings of the study suggest these three medicinal plant extracts can play a promising roleas antibacterial agents in against pathogenic bacteria.

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