Abstract

EVALUATION OF OXIDANT AND ANTIOXIDANT STATUS AMONG CHRONIC PERIODONTITIS PATIENTS AND HEALTHY SUBJECTS

Dr. Reshama Y. Sawant* and Dr. Chitra Y. Dhume

Abstract

Oxidative stress has been implicated in the pathogenesis of inflammatory condition like periodontitis. This study was carried out inorder to assess the levels of oxidants and antioxidants in the saliva sample of periodontitis patients and compare it with healthy subjects.this study comprised of 70 subjects, out of which 35 were chronic periodontitis patients and 35 were healthy subjects.saliva sample was obtained from all the subjects and analysed for levels of MDA which is a marker of oxidative stress. Also total antioxidant capacity(TAC) was determined ,alongwith individual antioxidants like vitamin C, uric acid and reduced glutathione. It was found that the levels of MDA was significantly increased in chronic periodontitis patients than healthy subjects (p

Keywords: Chronic periodontitis, MDA, Total antioxidant capacity, Uric acid.