Abstract

RISPERIDONE INDUCED PARKINSONISM

Persis Johnson*, Nivil Joseph, Neethu George and Jisna Thomas

Abstract

Risperidone, an antipsychotic drug which is used to treat schizophrenia and symptoms of bipolar disorder. Drug induced Parkinsonism is the second most common cause of Parkinsonism. Herein we have a case of risperidone induced Parkinsonism. A 25year male patient developed pill rolling tremor of upper limb more in right hand and rigidity in both upper limbs after taking the drug. The patient is a known case of mood disorder since 6 months and took risperidone 1.5mg twice daily. The symptoms persisted for several days even after stopping the drug. Based on his clinical presentation, we assume that the condition was result of risperidone. Causality assessment was also suggestive of a probable relationship between patient’s symptoms and use of risperidone. The clinical features of drug induced Parkinsonism and Parkinson’s disease are misdiagnosed as they appear to be indistinguishable. But the clinical manifestations of drug induced Parkinsonism is characterized as bilateral and symmetric Parkinsonism without tremor at rest.

Keywords: Risperidone, Drug induced Parkinsonism, Parkinsonism Disease, Antipsychotic drug, Tremor.