Abstract

A PHARMACOGNOSTICAL AND PHYSICO-CHEMICAL EVALUATION OF JEEVANIYA VATI IN THE MANAGEMENT OF VANDHYATVA (FEMALE INFERTILITY) W.S.R. ENDOMETRIAL FACTOR

Anmol Verma*, Dr. Shilpa B. Donga, Harisha C. R. and Shukla V. J.

Abstract

Infertility is defined as failure to conceive within one year or more than one year of regular & unprotected coitus. It is the most sensitive and cumbersome problem which haunts every couple. 10-15% world population affected by this problem. Among them Female is directly responsible about 30.20 %. The sub factors of female infertility are Ovarian, Endometrial, Tubal and Uterine etc. The endometrium (Garbhashaya) plays a major role in establishing a pregnancy and any alteration in this could be a potential cause for failure of implantation thus affecting fertility. Jeevaniya Gana is mentioned by Acharya Sharangdhara as Garbhasandhankrid. So this formulation was selected to see the effect on endometrial factor in form of Tablet. However, till date no published data is available on its analytical profile. The main aims and objectives of this study are to develop the pharmacognostical and phytochemical profile of Jeevaniya Vati. The pharmacognostical study reveals the presence of Lignified fibres, Prismatic crystals, Borderpitted vessels, Rhomboidal crystal, Scleroids, Stone cells etc. Pharmaceutical analysis showed that the loss on drying value was 8.245%, ash value was 8.9%w/w, water soluble extract was 46.3%, methanol soluble was 32.5%. HPTLC fingerprinting profile of Jeevaniya Vati revealed 7 spots at 254 nm and 5 spots at 366nm.

Keywords: HPTLC, Jeevaniya Vati, Pharmacognosy, Physicochemical.