Abstract

RESEARCH CARCINOGENIC EFFECT OF TARTRAZINE VS NITROGENOUS BASES BY THE QUANTUM METHOD (ZINDO/ 1).

Lázaro Balan-Rodriguez, Leonardo Tejero-Jimenez María Deyanira Loya-Vargas, Dr. Manuel González-Pérez*

Abstract

Tartrazine yellow dye whose structure tine trisodium salt of 3-carboxy- 5-hydroxy benzene pyrazolone-1 (p-sulfophenyl) - 4 - (sulfophenyl azo). Azo dyes have a group (-N = N-) in its chemical structure. In this research, the carcinogenic effect of tartrazine vs. nitrogenous bases by quantum method (Zindo/1) was determined. The simulations realized with molecular simulator Hyper Chem (HC). The specific parameters selected for each of the simulations were calculated by Semi-Empirical Method: ZINDO/1. Tartrazine has the lowest of all substances ETC because of its small ETC is the most chemically stable material. Interaction Guanine-Tartrazine has the lowest ETC 10.8431373, therefore, is most likely the interaction between compounds.

Keywords: Tartrazine, Cancer, Nitrogenous bases, Quantum method.