Abstract

SALIVARY BIOMARKERS AS A DIAGNOSTIC INDICATOR OF PERIODONTAL DISEASE - A REVIEW

Dr. R. Saranyan, MDS*, Dr. Rasila Sainu, Dr. D. Jayachandran, MDS, Dr. B, Manovijay, MDS, Dr. N. Sayee Ganesh, MDS, Dr. K. Priy, MDS,

Abstract

A biomarker is a naturally occurring molecule or a gene by which a particular pathological or physiological processes, diseases, etc can be identified. Genetically a biomarker is "anything that can be used as an indicator of a particular disease state or some other physiological state of an organism". Periodontitis is a multifactorial disease of the periodontium where the host releases a series of inflammatory mediators .Saliva is being used as a diagnostic fluid for analysis of periodontal disease as it is easy, rapid and non- invasive to collect , and readily abundant. This review deals with the various salivary biomarkers of periodontal disease and the diagnostic aids available for their detection.

Keywords: Periodontitis, saliva, biomarker, diagnostic aids.