Abstract

PHARMACOGNOSTICAL AND PRELIMINARY PHYSICO CHEMICAL ASSAY OF RASAYANA GRANULES – A PILOT STUDY

Dr. Prachi Sharma*, Dr. L. P. Dei, Shukla V. J., Harisha C. R., Namdev Vanganekar

Abstract

In Ayurveda context Acharya Sushruta has mentioned to take Shita, Madhura, Drava Ahara for Garbhini. Rasayana drugs also having these qualities and no side effects. Drug that nourishes, energizes & vitalizes are Rasayana drugs. The drugs are seasonal and pregnant women have taste variations along with morning sickness. As the powder is not palatable, its form has been converted in to granules form. Till date there is no scientific evaluation has been observed. An attempt is made to evaluate its Pharmacognostical and physicochemical profile. Pharmacognostically authenticated Rasayana drugs were used for the preparation of granules and it was analyzed through qualitative and quantitative analysis of physicochemical parameters. High-Performance Thin Layer chromatography study (HPTLC) was also developed. Pharmacognostical results shows that Stone cells of Jeevanti, Brown content of Draksha, Silica deposition of Amalaki, Chollenchyma cells of Guduchi & Acicular crystal of Shatavari etc is found. Qualitative study shows that ph is 6.5, ash value is 6.55% w/w, loss on drying is 1.945% w/w, water soluble extract is 78% w/w & alcohol soluble extract is 34.84% w/w. HPTLC study shows that Maximum 7 spots were obtained when viewed under short wave ultra violet light (254 nm) and 4 spots viewed under long wave ultra violet light (366 nm).

Keywords: Bala, Shatavari, Guduchi, Phytochemical Analysis, Chromatography.