Abstract

ETHANOLIC EXTRACT OF ALOE VERA TESTIS TISSUE IMPROVES LIPID METABOLISM PROFILES IN ALLOXAN INDUCED DIABETIC ALBINO MALE RATS

Dr. Ravi Naik Mude*

Abstract

The present investigate aims to examine the influence of Aloe vera in testis of Alloxan induced diabetic rats. Diabetes was induced by a single injection of Alloxan (40 mg/kg body weight). Aloe vera (300 mg/kg body weight) was treated to normal and diabetic rats for three weeks. Three month old male wistar were divided into 4 groups (n=6) namely: normal rats, normal + Aloe vera, diabetic, diabetic + Aloe vera. The present study, the protective use of Aloe vera on cholesterol, lipid peroxidation, Triglycerides levels in diabetic male albino-rats. The levels of cholesterol, lipid peroxidation, triglycerides in testis were increased significantly in diabetic rats. Oral administration of the Aloe vera leaf extract reduced significantly the levels of lipid metablolic profiles (cholesterol, lipid peroxidation, triglycerides). The Result of the study indicates that Aloe vera extract was effective in improving testis damage for diabetic rats. In conclusion, the Aloe vera extract played a key role in reduction of diabetic patients.

Keywords: Diabetes, Aloe vera, Alloxan, Lipid profiles, testis, male rats.