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WJPR

World Journal of Pharmaceutical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

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Abstract

â€•FORMULATION DEVELOPMENT & EVALUATION OF FAST DISSOLVING TABLET OF RIZATRIPTAN BENZOATEâ€

Kishor Rodge*, R. S. Moon and Swapnil Waghmare

Abstract

The purpose of this investigation was to to develop fast dissolving tablet of Rizatriptan Benzoate using various concentration of disintegrants and superdisintegrants along with directly compressible excipients. Rizatriptan benzoate use to treat migraines. Fast dissolving tablet of Rizatriptan benzoate containing crospovidone-xl, croscarmellose sodium, avicel PH-102, aspartame, magnesium Stearate, Aerosil, menthol, pearlitol SD-200 The formulation were evaluated for disintegration time, in vitro dissolution, hardness, friability, weight variation and thickness, water absorption ratio.

Keywords: superdisintegrant, Fast dissolving Tablet, Migraine, Rizatriptan benzoate.

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