Abstract

ANTIOXIDANT ACTIVITY OF CYATHULA PROSTRATE, IPOMEA OBSCURA AND MARSILEA QUADRIFOLIA IN NEPHROTOXICITY INDUCED MALE ALBINO RATS.

D. Eazhisai Vallabi* and V. Elango

Abstract

This present study deals with the anti oxidant activity in Cyathula prostratae (whole part), Ipomea obscura (leaves), Marsilea quadrifolia (leaves). The selected plant was collected, shade dried and made into powder. Anti oxidant activity was evaluated in gentamicin induced rats. From these results it can be understood that plant crude showing its pharmacological action on nephrotoxic rats after gentamicin administration. This is exactly what the action that is being observed from the drug induced group which also shown its action in the plants treated group. From these results it can be understood that the plant powder has antioxidant activity against gentamicin nephrotoxic induced rats.

Keywords: antioxidant, ROS, gentamicin, nephrotoxicity, LPO, SOD, Gpx.